IL-17 anticorps

N° du produit ABIN2474946

Cet anticorps anti-IL-17 est un anticorps Rat Monoclonal détectant IL-17 dans WB, ELISA et FACS. Adapté pour Souris.

Aperçu rapide pour IL-17 anticorps (ABIN2474946)

Antigène: IL-17 (IL17) (Interleukin 17 (IL17))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-17 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Clone: TC11-18H10

Détail du produit anti-IL-17 anticorps

Specificité: This antibody recognises mouse Interleukin 17, a 32 kDa disulfide-linked homodimer consisting of two 136 amino acid chains, which belong to the IL-17 family (classified as IL-17A to IL-17F), and signal through the IL-17 receptor (IL-17R/CDw217). IL-17 is produced primarily by activated CD4+ T cells and induces a variety of target cells to secrete inflammatory cytokines, including IL-1beta, IL-6, TNFalpha, IFNgamma and granulocyte colony-stimulating factor, as well as synergizing with other inflammatory cytokines and agonists. The role of IL-17 in bone metabolism has become a focus area for studies into Rheumatoid Arthritis, in which levels of IL-17 are significantly increased and may contribute to bone destruction.

Attributs du produit: Purified IgG

Purification: Purified

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Détails sur IL-17

Antigène: IL-17 (IL17) (Interleukin 17 (IL17))

Autre désignation: IL-17

Sujet: Synonyms: IL-17A